Amyloid A Amyloidosis
نویسندگان
چکیده
منابع مشابه
Amyloid A Amyloidosis Secondary to Rheumatoid Arthritis
Amyloids are insoluble fibrous protein aggregates sharing specific structural traits. Abnormal accumulation of amyloid in organs may lead to amyloidosis, and may play a role in various diseases. The name amyloid comes from the early mistaken identification of the substance as starch (amylum in Latin), based on crude iodine-staining techniques. For a period, it was debated whether or not amyloid...
متن کاملClinical Presentation of Amyloid A Amyloidosis
Amyloid is an eosinophilic substance which appears “apple-green birefringence” in Congo red stained tissue sections under polarized light. This standard histological analysis is supported with immunochemistry technic using specific antibodies directed against most of the common human amyloid proteins, and also amyloid proteins can be identified with characteristic fibrillar appearance by electr...
متن کاملIs amyloid A (AA) amyloidosis always secondary?
The case is reported of a patient with systemic AA amyloidosis associated with non-specific mesenteric lymphadenitis and chronic sideropenia. Renal, small bowel, and rectal biopsies showed amyloid deposits containing AA protein, as defined by potassium permanganate sensitivity and by reactivity with AA antiserum. Reversal of the nephrotic syndrome occurred during steroid-azathioprine therapy.
متن کاملAmyloid A amyloidosis with subcutaneous drug abuse
INTRODUCTION Amyloid A (AA) amyloidosis is a systemic form of amyloidosis secondary to chronic infections and inflammatory disorders. An acute-phase protein produced by the liver, serum amyloid A (SAA) is the precursor of AA amyloid fibrils. AA amyloid deposition occurs predominantly in the kidneys, spleen, adrenal glands, liver and gastrointestinal tract. The manifestations of AA amyloidosis i...
متن کاملPathogenetic mechanisms of amyloid A amyloidosis.
Systemic amyloid A (AA) amyloidosis is a serious complication of chronic inflammation. Serum AA protein (SAA), an acute phase plasma protein, is deposited extracellularly as insoluble amyloid fibrils that damage tissue structure and function. Clinical AA amyloidosis is typically preceded by many years of active inflammation before presenting, most commonly with renal involvement. Using dose-dep...
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ژورنال
عنوان ژورنال: Veterinary Pathology
سال: 2016
ISSN: 0300-9858,1544-2217
DOI: 10.1177/0300985816677150